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Sleeping Disorders

Biological and clinical insights from genetics of insomnia symptoms
Genome-wide association analyses identify 57 loci associated with insomnia symptoms and provide evidence of shared…
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Short sleep duration and cardiometabolic risk: from pathophysiology to clinical evidence
This Review describes the effects of short sleep duration on cardiovascular health and diseases, and the authors discuss the main pathophysiological mechanisms involved, taking into account both experimental data and clinical evidence.
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Neural network analysis of sleep stages enables efficient diagnosis of narcolepsy
The diagnosis of sleep disorders such as narcolepsy and insomnia currently requires experts to interpret sleep recordings (polysomnography). Here, the authors introduce a neural network analysis method for polysomnography that could reduce time spent in sleep clinics and automate narcolepsy diagnosis
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Sleep history predicts late-life Alzheimer's pathology
Findings suggest novel, sleep-based diagnosis and treatment methods

Sleep patterns can predict the accumulation of Alzheimer's pathology proteins later in life, according to a new study of older men and women published in JNeurosci. These findings could lead to new sleep-based early diagnosis and prevention measures in the treatment of Alzheimer's disease.
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